Quality of life in gynecologic cancer survivors compared to healthy check-up women.
10.3802/jgo.2011.22.2.103
- Author:
Sarikapan WILAILAK
1
;
Arb aroon LERTKHACHONSUK
;
Nawaporn LOHACHAROENVANICH
;
Suteera Chukkul LUENGSUKCHAROEN
;
Manmana JIRAJARAS
;
Puchong LIKITANASOMBAT
;
Suwannee SIRILERTTRAKUL
Author Information
1. Department of Obstetrics and Gynecology, Ramathibodi Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand. sarikapanw@gmail.com
- Publication Type:Original Article
- Keywords:
Quality of life;
Functional Assessment of Cancer Therapy-General;
Gynecologic cancer
- MeSH:
Caregivers;
Educational Status;
Female;
Follow-Up Studies;
Humans;
Mass Screening;
Multivariate Analysis;
Quality of Life;
Spouses;
Survivors;
Surveys and Questionnaires
- From:Journal of Gynecologic Oncology
2011;22(2):103-109
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The primary objective of this study was to compare quality of life of disease-free patients after therapy for gynecologic malignancies at follow-up in comparison with healthy check-up patients. Our second objective was to assess correlation between demographic data, disease and treatment factors and quality of life scores. METHODS: Patients completed the Functional Assessment of Cancer Therapy-General (FACT-G) quality of life questionnaire at least 6 months after treatment for a gynecologic malignancy. Responses were compared to unmatched healthy women who were seen for standard gynecologic screening examinations. Statistical calculation was done using chi-squared tests, Wilcoxon rank-sum, and Kruskal-Wallis one-way analysis and Spearman rank correlations. Factors associated with FACT-G scores were evaluated using univariate and multivariate analyses. RESULTS: Eight hundred and seventy patients were recruited. The median time since therapy was 61 months (range, 6 to 173 months). The overall FACT-G scores were higher in the patient group than in the healthy group (p<0.05). The scores of each subscale measuring physical, functional, social/family and emotional well-being were also higher in the patient group (p<0.05). Multivariate analysis revealed correlation between Eastern Cooperative Oncology Group performance status, educational level, care giver, presence of economic problems and FACT-G scores. CONCLUSION: The quality of life scores were higher in gynecologic cancer patients after treatment. And the factors that associated with the higher score in the patient group are having husband as a caregiver, no financial problem, Eastern Cooperative Oncology Group score 0 or 1 and having high school or higher education.