A Case Report of Recurrent Malignant Paraganglioma with Lung and Spine Metastasis that Occurred Sixteen Years after Primary Tumor Excision.
10.3904/kjm.2014.87.4.484
- Author:
Eul Sun MOON
1
;
Hye Sook MIN
;
Chang Ho JUNG
;
Jong Hyun CHOI
;
Jun Suk KIM
;
Hye Jin YOO
;
Sang Yong CHOI
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. deisy21@naver.com
- Publication Type:Case Report
- Keywords:
Malignant paraganglioma, Lung metastasis, Spine metastasis;
Metaiodobenzylguanidine;
Chemotherapy
- MeSH:
3-Iodobenzylguanidine;
Chromaffin Cells;
Drug Therapy;
Lung*;
Neoplasm Metastasis*;
Paraganglioma*;
Radiotherapy;
Spine*
- From:Korean Journal of Medicine
2014;87(4):484-490
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Paragangliomas are rare tumors that arise from the extra-adrenal chromaffin cells, and malignancy is defined by the presence of metastases to sites that normally lack chromaffin tissue. The main therapeutic targets are tumor reduction and control of excessive catecholamine secretion. Currently, the adjuvant therapy to surgery is radiotherapy treatment using high-dose MIBG; chemotherapy is currently evolving. We report herein a case of malignant paraganglioma with lung and spine metastasis that occurred 16 years after primary tumor excision and was treated with high dose MIBG radiotherapy and chemotherapy.
