A Case of Delayed Hypersensitivity to Enoxaparin in Patient with Deep Vein Thrombosis.
- Author:
Seung Wook JWA
1
;
Sung Jun KIM
;
Hyun Chang KO
;
Moon Bum KIM
;
Kyung Sool KWON
;
Chang Keun OH
Author Information
1. Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea. ckoh@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Deep vein thrombosis;
Delayed hypersensitivity;
Enoxaparin
- MeSH:
Angioedema;
Enoxaparin*;
Hemorrhage;
Heparin;
Heparin, Low-Molecular-Weight;
Humans;
Hypersensitivity, Delayed*;
Necrosis;
Skin;
Skin Manifestations;
Urticaria;
Venous Thrombosis*
- From:Korean Journal of Dermatology
2007;45(8):851-854
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Enoxaparin, a low-molecular-weight heparin, is widely used to prevent and treat thromboembolic diseases due to its improved pharmacodynamic properties and better safety profile than unfractionated heparins. Although the most common complication is bleeding, enoxaprin has also been implicated in skin manifestations such as urticaria, bruising, angioedema and skin necrosis. Rarely, cases have been reported of eczema-like plaques caused by delayed hypersensitivity after administration of enoxaparin injections. However, there is no report to describe delayed hypersensitivity to enoxaparin in Korean literature. We present herein a case of delayed hypersensitivity to enoxaparin, which is very rare case but needs the attention of special departments such as dermatologists as well as internalists and phlebologists.
