Grading System for Gastric Epithelial Proliferative Diseases Standardized Guidelines proposed by Korean Study Group for Pathology of Digestive Diseases.
- Author:
Hoguen KIM
;
So Young JIN
;
Ja June JANG
;
Woo Ho KIM
;
Sang Yong SONG
;
Kyu Rae KIM
;
Eun Sil YU
;
Hyung Sik SHIN
;
Han Kyeom KIM
;
Jin Hee SOHN
;
Eun Kyung HONG
;
Youn Wha KIM
;
Jin Sook JEONG
;
Chang Jin KIM
;
Shin Eun CHOI
;
In Suh PARK
;
Chan Il PARK
;
Yong Il KIM
- Publication Type:Original Article
- Keywords:
Gastric epithelial proliferative diseases;
Dysplasia;
Grading system
- MeSH:
Biopsy;
Consensus;
Diagnosis;
Epithelium;
Pathology*
- From:Korean Journal of Pathology
1997;31(5):389-400
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The assessment of epithelial changes in gastric mucosal biopsies has been one of the major problems caused by inconsistencies in and disagreements about nomenclature and interpretation. To resolve these issues, members of the Study Group for Pathology of Digestive Diseases reviewed microslides of 50 gastric lesions showing varying degrees of mucosal abnormality and reached the following consensus; 1) the proliferating gastric epithelium can be divided into hyperplastic and neoplastic; 2) the term "dysplasia" is reserved for the microscopic epithelial changes that are unequivocally neoplastic; 3) Biopsy specimens can be categorized as regenerative(negative for dysplasia), indefinite(questionable dysplasia), positive(positive for dysplasia) and overt carcinoma; 4) The positive category can be divided into two subgroups, high grade dysplasia and low grade dysplasia. Criteria for each grade are presented and discussed. We offer these guidelines for establishing the correct diagnosis of the gastric mucosal biopsy specimens and for prospective studies.
