Distinguishing Quantitative Electroencephalogram Findings between Adjustment Disorder and Major Depressive Disorder.
- Author:
Hyun Ghang JEONG
1
;
Young Hoon KO
;
Changsu HAN
;
Yong Ku KIM
;
Sook Haeng JOE
Author Information
1. Department of Psychiatry, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
- Publication Type:Original Article
- Keywords:
Adjustment disorder;
Major depressive disorder;
Electroencephalography;
Computer-assisted signal processing;
Power;
Coherence
- MeSH:
Adjustment Disorders;
Axis, Cervical Vertebra;
Depressive Disorder, Major;
Electrodes;
Electroencephalography;
Humans;
Signal Processing, Computer-Assisted
- From:Psychiatry Investigation
2013;10(1):62-68
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Adjustment disorder (ADJ) is a common diagnosis. However, it is difficult to distinguish ADJ from other major Axis I disorders, such as major depressive disorder (MDD). The aim of this study was to determine the distinguishing neurophysiological characteristics between ADJ and MDD using quantitative analysis of an electroencephalogram (QEEG). METHODS: The study included 30 patients with ADJ and 51 patients with MDD. Resting (eye closed) vigilance controlled EEG recordings were assessed at 19 electrode sites according to the international 10/20 system. QEEG absolute power and coherence were calculated for the delta, theta, alpha and beta bandwidths. RESULTS: Absolute powers of alpha and high beta bands, particularly at the frontocentral area, differed between MDD and ADJ group (p<0.05). Interhemispheric coherence values for the delta and beta bands were lower in the ADJ group than in the MDD group (p<0.05). Intrahemispheric coherence values for the alpha band were also lower in the ADJ group (p<0.05). CONCLUSION: The differences in QEEG power and coherence in our investigation suggest that underlying pathophysiologic mechanisms may be different between ADJ and MDD.
