Patient Controlled Analgesia of Alfentanil after a Total Abdominal Hysterectomy: A Comparison of the Intravenous and Epidural Route.
10.3344/kjp.2007.20.2.169
- Author:
Soo Kyeong CHOI
1
;
Seok Hwa YOON
;
Jun Hwa LEE
;
Jae Ha HWANG
;
Woo Suk JUNG
;
Yoon Hee KIM
;
Won Hyung LEE
Author Information
1. Department of Anesthesia and Pain Medicine, Eulji Hospital, College of Medicine, Eulji University, Seoul, Korea.
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
alfentanil;
patient controlled analgesia;
side effects
- MeSH:
Alfentanil*;
Analgesia;
Analgesia, Epidural;
Analgesia, Patient-Controlled*;
Blood Pressure;
Double-Blind Method;
Heart Rate;
Humans;
Hysterectomy*;
Incidence;
Pain, Postoperative
- From:The Korean Journal of Pain
2007;20(2):169-173
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Although the use of intravenous patient controlled analgesia (IVPCA) has been compared to the use of patient conrolled epidural analgesia (PCEA), there is no optimal administration route of alfentanil for the treatment of postoperative pain. This randomized double-blind study compared the efficacy of the use of IVPCA and PCEA for postoperative pain and the side effects after a total abdominal hysterectomy (TAH). METHODS: Sixty patients undergoing a TAH were randomly assigned to receive either IVPCA (Group I) or PCEA (Group E) for the infusion of alfentanil for postoperative pain control. In both groups, a loading dose of 750 microgram alfentanil was administered. All patients received the same continuous infusion rate (0.3 mg/h), bolus dose (0.15 mg), and lockout time (15 min). The incidence of side effects, the VAS (visual analog scale) of pain, blood pressure, and heart rate were checked for 20 hours after the loading dose injection. RESULTS: The VAS of pain was not significantly different between the two groups of patients. The onset of the analgesic effect was significantly more rapid in the Group I patients than in the Group E patients. There was no difference in side effects for either group. CONCLUSIONS: When considering multiple factors such as the onset of analgesia, technical difficulties or infection after the procedure, IVPCA using alfentanil is more useful than PCEA for postoperative pain control after a TAH.
