Clinical Outcomes of Penetrating Keratoplasty and Limbal Transplantation from the Same Versus Different Donor Graft.
- Author:
Mee Kum KIM
1
;
Jae Lim LEE
;
Won Ryang WEE
;
Jin Hak LEE
Author Information
1. Department of Ophthalmology, Seoul Municipal Boramae Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Limbal allograft transplantation;
Penetrating keratoplasty;
Different donors;
Same donors;
Endothelial rejection
- MeSH:
Allografts;
Burns, Chemical;
Epithelium;
Follow-Up Studies;
Graft Rejection;
Humans;
Keratoplasty, Penetrating*;
Stevens-Johnson Syndrome;
Tissue Donors*;
Transplants*;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2002;43(9):1605-1611
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the difference of the central graft rejection after penetrating keratoplasty and limbal allograft transplantation from different donors vs from the same donor. MATERIAL and METHODS: Three patients diagnosed with chemical burn and one with Stevens-Johnson syndrome were included. Three patients underwent penetrating keratoplasty and limbal allograft transplantation from different donors and one underwent the same operation from the same donor. Mean follow-up was 13 months. Visual acuity, re-epithelization and endothelial rejection were examined. RESULTS: Re-epithelization occurred within 3 to 14 days (mean 8.7 days) in three eyes with chemical burn. Visual acuities ranged from light perception to 20/100. Endothelial rejection developed in the eye transplanted from the same donor. Re-epithelization failed in the eye with Stevens-Johnson syndrome even though limbal graft transplantation and cultivated limbal epithelium transplantation were performed repeatedly. CONCLUSIONS: Corneal endothelial rejection seemed to decrease after penetrating keratoplasty and limbal allograft transplantation from different donors.
