One case of Kartagener's syndrome with extracemtral microtubule in cilia.
- Author:
Chang Hyeok AN
1
;
Jae Chul CHOI
;
Byung Hun LEE
;
Yong Bum PARK
;
Hyun Suk JEE
;
Sung Jin PARK
;
Jae Yeol KIM
;
In Won PARK
;
Byoung Whui CHOI
;
Sung Ho HUE
Author Information
1. Department of Internal Medicine, College of Medicine, Chung-Ang University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Helicobacter pylori;
Apoptosis;
Ammonia
- MeSH:
Ammonia;
Apoptosis;
Arm;
Bronchiectasis;
Cilia*;
Dyneins;
Epithelium;
Helicobacter pylori;
Humans;
Kartagener Syndrome*;
Microscopy, Electron;
Microtubules*;
Mucociliary Clearance;
Nasal Mucosa;
Sinusitis;
Situs Inversus;
Sperm Tail
- From:Korean Journal of Medicine
2000;59(2):230-234
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kartagener's syndrome is an autosomal recessively inherited condition characterized by triad of situs inversus, bronchiectasis, and chronic sinusitis. And recently it was classified as a subclass of dyskinetic cilia syndrome, which has a defect in mucociliary transport resulting from immotile or dyskinetic beating of cilia. Electron microscopic examination of the cilia from sperm tails, nasal and bronchial epithelium of patients reveals the partial or the complete absence of dynein arms or radial spoke, or microtubule disposition. This patient had all the triad of Kartagener's syndrome and showed two extracentral microtubules on the electron microscopic examination of the nasal mucosa. Most patients have dynein arms defect, but it is rare to have extracentral microtubules. So we report one case of Kartagener's syndrome with extracentral microtubules confirmed by electron microscopy.
