Intracranial granulocytic sarcoma (chloroma) in a nonleukemic patient.
10.3346/jkms.1987.2.3.173
- Author:
Dong Heon YOON
1
;
Kyung Ja CHO
;
Yeon Lim SUH
;
Chul Woo KIM
;
Je G CHI
;
Dae Hee HAN
;
Young Joo BANG
;
Byung Kook KIM
;
Noe Kyeong KIM
;
Han Ik CHO
Author Information
1. Department of Pathology, College of Medicine, Seoul National University, Korea.
- Publication Type:Case Reports
- Keywords:
Chloroma;
granulocytic sarcoma;
acute myelogenous leukemia
- MeSH:
Adolescent;
Brain Neoplasms/pathology/*surgery;
Female;
Humans;
Leukemia, Myeloid/pathology/*surgery
- From:Journal of Korean Medical Science
1987;2(3):173-178
- CountryRepublic of Korea
- Language:English
-
Abstract:
Chloroma is a granulocytic sarcoma with it's characteristic greenish color. Recently there is an increased number of cases that are apparently aleukemic when the tumor mass is first presented. Recently we experienced a case of granulocytic sarcoma with characteristic green color (chloroma), which showed no evidence of leukemia in the bone marrow and peripheral blood. This patient presented headache, and was diagnosed brain tumor on computed tomography. A left parietal cranietomy was done to remove a large central dome-like mass, 8 cm, involving the dura with a slightly dusky greenish solid appearance. Compact nests of moderately mature granulocytes and immature cells comprised the tumor. Histochemical and electron microscopic studies confirmed these tumor cells as myeloid cells in varying stages of maturation. Several days after the operation, left cervical lymph nodes became palpated, and the biopsied lymph nodes revealed same neoplastic cells seen in the skull. However, bone marrow aspiration, biopsy and peripheral blood smears did not show any evidence of leukemia.
