Liver cell adenoma in a neonate: report of an autopsy case.
10.3346/jkms.1987.2.3.189
- Author:
Yeon Lim SUH
1
;
Hyung Geun SONG
;
Je G CHI
Author Information
1. Department of Pathology, Seoul National University Children's Hospital, College of Medicine, Korea.
- Publication Type:Case Reports
- Keywords:
Liver cell adenoma;
benign tumor;
liver;
neonate
- MeSH:
Adenoma/*pathology;
Female;
Humans;
Infant;
Infant, Newborn;
Infant, Newborn, Diseases/*pathology;
Liver Neoplasms/*pathology
- From:Journal of Korean Medical Science
1987;2(3):189-194
- CountryRepublic of Korea
- Language:English
-
Abstract:
A case of liver cell adenoma that was incidentally found at postmortem examination of a neonate who died of E. coli sepsis is described. The adenoma was a sharply demarcated, not encapsulated mass located subcapsularly in the right lobe, and was pale tan to light yellowish round nodule of 0.9 cm in diameter. Microscopically, the tumor was composed of sheets and cords of uniform and slightly enlarged hepatocytes separated by dilated sinusoids. There were no portal zones or central veins to suggest the normal lobular architecture. The nuclei were bland and the cytoplasm varied from clear to acidophilic, containing lipid vacuoles. Ultrastructural examination showed that the hepatocytes of the tumor had highly differentiated organelles, reminiscent of normal hepatocytes.
