Infantile hemangioendothelioma of the liver: a case report.
10.3346/jkms.1987.2.3.195
- Author:
Yeon Lim SUH
1
;
Kyung Ja CHO
;
Je G CHI
;
Kwi Won PARK
Author Information
1. Department of Pathology, Seoul National University Children's Hospital, College of Medicine, Korea.
- Publication Type:Case Reports
- Keywords:
Hemangioendothelioma;
vascular tumor;
liver;
infant;
neoplasm
- MeSH:
Hemangioendothelioma/*pathology/surgery;
Humans;
Infant;
Liver Neoplasms/*pathology/surgery;
Male
- From:Journal of Korean Medical Science
1987;2(3):195-200
- CountryRepublic of Korea
- Language:English
-
Abstract:
A case of type 1 infantile hemangioendothelioma of the liver in a 3 month old male infant who had an abdominal mass incidentally noted at 40 days of age, is described. Grossly, the tumor showed a well circumscribed, pinkish gray and gelatinous mass with areas of central necrosis, multifocal thrombi and hemorrhages, and small cysts. Microscopically, the lesion consisted of numerous vascular channels of various size lined by a single layer of flat or plump endothelial cells. Areas of infarction, thrombosis and calcification, and formation of cavernous hemangiomatous foci were also noted in the lesion. Ultrastructurally, the cells had the characteristics of endothelium, including basal lamina, pinocytic vesicles, and Weibel-Palade bodies. Factor VIII-associated antigen was demonstrated in the tumor cells.
