A Case of Essential Cryoglobulinemic Neuropathy.
- Author:
Sang Soo LEE
1
;
Myung Ja SONG
;
Ho Seong HAN
;
Dong Ick SHIN
;
Sung Hyun LEE
Author Information
1. Department of Neurology, College of Medicine, Chungbuk National University, Korea. sslee@chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Cryoglobulinemia;
Vasculitic neuropathy;
Mononeuritis multiplex
- MeSH:
Adult;
Arthralgia;
Autoimmune Diseases;
Axons;
Biopsy;
Cryoglobulinemia;
Female;
Humans;
Liver Diseases;
Mononeuropathies;
Purpura
- From:Journal of the Korean Neurological Association
2007;25(2):247-250
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mixed cryoglobulinemia occurs predominantly in association with chronic liver disease, infections, autoimmune diseases, and malignancies. Mixed cryoglobulinemia is classified as essential if no primary disease is identified. We report a 42-year-old woman with a painful essential cryoglobulinemic neuropathy. She developed arthralgia, purpura, and subacute multifocal sensorimotor neuropathy. Laboratory studies did not show any associated conditions except for an elevated cryoglobulin level. An electrophysiological study and nerve biopsy were indicative of multifocal axonal neuropathy. The neuropathy was stabilized with immunosuppressive treatment.