A Case of Cap Polyposis Successfully Managed with Infliximab.
- Author:
Dong Il KIM
1
;
Yoon Tae JEEN
;
Sang Hoon PARK
;
Hwang Rae CHUN
;
Chang Won BAECK
;
Yong Sik KIM
;
Hoon Jai CHUN
;
Hong Sik LEE
;
Soon Ho UM
;
Jai Hyun CHOI
;
Chang Duck KIM
;
Ho Sang RYU
;
Bong Kyung SHIN
;
Jin Hai HYUN
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. ytjeen@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Cap polyposis;
Infliximab;
Pseudomembranous colitis
- MeSH:
Colitis;
Diarrhea;
Drug Therapy;
Enterocolitis, Pseudomembranous;
Exudates and Transudates;
Female;
Humans;
Middle Aged;
Pathology;
Polyps;
Rectum;
Recurrence;
Infliximab
- From:Korean Journal of Gastrointestinal Endoscopy
2005;31(3):180-184
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cap polyposis is a rare disorder characterized by bloody, mucoid diarrhea with rectosigmoid polyps covered by a cap of fibrinopurulent exudate. The etiology and pathogenesis of cap polyposis is unknown, and no specific treatment has been established. Drug therapies are usually unsuccessful. Patients with a solitary cap polyp respond well to endoscopic polypectomy, while patients with multiple polyps and concurrent anorectal pathology require surgical resection. However, rapid recurrence has been described after a limited surgical resection, and this necessitates panproctocolectomy. We report a case of a 58-year-old female diagnosed as cap polyposis on rectum with similar clinical and endoscopic features of pseudomenbranous colitis successfully treated with infliximab (murine chimeric monoclonal antibody to TNF-alpha).
