The Role of Pulmonary Circulation in the Metabolism of Atrial Natriuretic Factor in Man.
10.4070/kcj.1988.18.4.553
- Author:
Jung Don SEO
;
Hyo Soo KIM
;
Seong Wook PARK
;
Kyu Hyung RYU
;
Cheol Ho KIM
;
Byung Hee OH
;
Young Bae PARK
;
Bo Yeon CHO
;
Yun Shik CHOI
;
Young Woo LEE
- Publication Type:Original Article
- Keywords:
Atrial natriuretic factor;
Pulmonary circulation
- MeSH:
Aorta;
Atrial Natriuretic Factor*;
Capillaries;
Cardiac Catheterization;
Cardiac Catheters;
Coronary Sinus;
Foramen Ovale;
Heart Atria;
Humans;
Metabolism*;
Myocardium;
Plasma;
Pulmonary Artery;
Pulmonary Circulation*;
Pulmonary Veins;
Veins
- From:Korean Circulation Journal
1988;18(4):553-558
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To evaluate the role pulmonary capillary in the metabolism of atrial natriuretic factor(ANF), we measured plasma level of immunoreative(IR) ANF in pulmonary artery, pulmonary vein, left atrium and aorta simultaneously in 7 cardiac patients with patent with foramen ovale without shunt and 8 cardiac patients with atrial septal defect(ASD) with only left to right shunt during cardiac catheterization. Plasma level of IR-ANF in pulmonary vein was significantly lower to be involved in the metabolism of ANF and that ANF secreted by left atrial myocardium is mainly drained through coronary sinus into right atrial cavity rather than directly into left atrial cavity through thebesian vein.
