A Case of Bacteremia by Neisseria gonorrhoeae Coincident with Massive Hemorrhage of Esophageal Varices.
10.3343/kjlm.2011.31.2.118
- Author:
Dahae WON
1
;
Dongheui AN
;
Mi Na KIM
;
Young Sang LEE
Author Information
1. Department of Laboratory Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. mnkim@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Neisseria gonorrhoeae;
Bacteremia;
Esophageal varices;
Hemorrhage
- MeSH:
Adult;
Bacteremia/complications/*diagnosis/microbiology;
Catalase/metabolism;
Esophageal and Gastric Varices/complications/*diagnosis;
Gastrointestinal Hemorrhage/*etiology;
Gonorrhea/complications/*diagnosis/microbiology;
Humans;
Ligation;
Liver Cirrhosis/diagnosis;
Male;
Neisseria gonorrhoeae/genetics/*isolation & purification;
Oxidoreductases/metabolism;
RNA, Ribosomal, 16S/chemistry/genetics;
Sequence Analysis, DNA
- From:The Korean Journal of Laboratory Medicine
2011;31(2):118-121
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 42-yr-old man with hepatitis B virus associated liver cirrhosis was admitted to the emergency room because of multiple seizures, a history of chills and myalgia over the previous 2 weeks, and 3 days of melena. He was febrile with a temperature of 38.0degrees C. There were no symptoms and signs related to the genitourinary system, skin, or joints. Three sets of blood cultures were obtained and oxidase-positive, gram-negative diplococci were detected after 25.9-26.9 hr of incubation in all aerobic vials. The organism was positive for catalase and oxidase, and was identified as Neisseria gonorrhoeae, using a Vitek Neisseria-Haemophilus Identification card (bioMerieux Vitek, Inc., USA). Further, 16S rRNA sequencing of this isolate revealed a 99.9% homology with the published sequence of N. gonorrhoeae strain NCTC 83785 (GenBank Accession No. NR_026079.1). Acute bleeding by variceal rupture seems to be a likely route of introduction of N. gonorrhoeae from the mucosa into the blood. To the best of our knowledge, this is the first case of gonococcal bacteremia in Korea.
