Treatment Outcomes after Endoscopic Submucosal Dissection of Large Superficial Rectosigmoid Colon Tumors.
- Author:
Jin Sung KOH
1
;
Jong Jae PARK
;
Wonho JUNG
;
Joon Young LEE
;
Sang Ah LIM
;
Minjung KWON
;
Hyejin NOH
;
Moon Kyung JOO
;
Beom Jae LEE
;
Ji Hoon KIM
;
Jong Eun YEON
;
Jae Seon KIM
;
Kwan Soo BYUN
;
Young Tae BAK
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Guro Hospital, Korea University College of Medicine, Seoul, Korea. gi7pjj@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Endoscopic submucosal dissection;
Large superficial tumor;
Rectosigmoid colon;
Outcomes
- MeSH:
Adenocarcinoma;
Adenoma;
Colon;
Colorectal Neoplasms;
Follow-Up Studies;
Hemorrhage;
Humans;
Medical Records
- From:Korean Journal of Gastrointestinal Endoscopy
2011;42(4):222-227
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Endoscopic submucosal dissection (ESD) of a colorectal tumor is technically difficult. This study aimed to analyze the clinical outcomes of superficial large rectosigmoid tumors after ESD. METHODS: Medical records of 15 patients with large rectosigmoid tumors (more than 30 mm), in which ESD performed, were reviewed retrospectively. RESULTS: The mean tumor size was 42.5+/-14.3 mm (range, 30~78 mm). A histological examination revealed a well-differentiated adenocarcinoma in five cases (33.3%), adenoma with high-grade dysplasia in six cases (40%), and low-grade dysplasia in four cases (26.7%). The mean procedural time was 90.5+/-60.7 min (range, 22~246 min). The en bloc resection rate was 86.7%, and the complete resection rate 100%. The lateral resection margin was positive in four cases (26.6%), but no cases with a positive vertical margin were observed. Bleeding occurred in three cases (20%), and all were treated successfully using endoscopic measures. Perforations occurred in three cases (20%); two cases were treated by clipping and the other by a laparotomy. CONCLUSIONS: ESD is a treatment option for superficial large rectosigmoid tumors. Further studies with larger cases and a longer term follow-up are needed to establish the efficacy and safety of ESD for colorectal tumors.
