Sigmoid Colon Cancer with Isolated Metastasis to the Left Kidney.
- Author:
Hyung Jin KIM
1
;
Ho Joong CHOI
;
Won Kyung KANG
;
Soon Nam OH
;
Chan Kwon JUNG
;
Seong Taek OH
Author Information
1. Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. wonkkang@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Sigmoid colon cancer;
Kidney metastasis;
Nephrectomy;
Synchronous cancer
- MeSH:
Chemotherapy, Adjuvant;
Colon, Sigmoid*;
Diagnosis;
Drug Therapy;
Female;
Fluorouracil;
Humans;
Kidney*;
Leucovorin;
Liver;
Middle Aged;
Neoplasm Metastasis*;
Nephrectomy;
Quality of Life;
Sigmoid Neoplasms*;
Tomography, X-Ray Computed
- From:Journal of the Korean Society of Coloproctology
2006;22(5):346-349
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report the case of a 63-year-old female with sigmoid colon cancer and isolated metastasis to the left kidney at the time of initial diagnosis. An anterior resection of the sigmoid colon and a left nephrectomy were performed. Three cycles of adjuvant chemotherapy consisting of oxaliplatin, 5-fluorouracil, and leucovorin were given, but two months after the surgery, multiple metastases of the liver were detected on a CT scan. The patient refused further treatment and died 5 months after the discovery of an isolated metastasis. An isolated metastasis to the kidney is very rare in clinical practice. A nephrectomy for kidney metastasis has no effect on survival and quality of life, and a nephrectomy may also compromise the choice of chemotherapy agents that require renal clearance; thus, a careful evaluation of renal function is necessary before a nephrectomy. At present, kidney metastasis should be regarded as an advanced metastatic disease, and aggressive chemotherapy, including target therapy, should prolong survival and improve the quality of life. However, when a synchronous or a metachronous renal tumor is suspected, a nephrectomy should be performed for accurate diagnosis and treatment.
