A Case of Sclerosing Cholangitis Showing Response to Prednisolone.
- Author:
Yo Sig SHIN
1
;
Yong Seok JANG
;
Min Kyoung KANG
;
Byoung Kuk JANG
;
Kyung Sik PARK
;
Jae Seok HWANG
;
Jung Hyeok KWON
;
Yu Na KANG
Author Information
1. Department of Internal Medicine, Keimyung University College of Medicine, Daegu, Korea. seenae99@dsmc.or.kr
- Publication Type:Case Report ; English Abstract
- Keywords:
Sclerosing cholangitis;
Immunoglobulin G4 associated cholangitis;
Prednisolone
- MeSH:
Adult;
Anti-Inflammatory Agents/*therapeutic use;
Cholangiopancreatography, Endoscopic Retrograde/methods;
Cholangitis, Sclerosing/*diagnosis/pathology;
Humans;
Male;
Prednisolone/*therapeutic use;
Treatment Outcome
- From:The Korean Journal of Gastroenterology
2007;50(6):402-406
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive fibrosis and destruction of intra- and extrahepatic bile ducts resulting in hepatic failure and death. Only the liver transplantation is the possible treatment for patients to survive. There has been a few reports that steroid is an effective treatment in autoimmune variant sclerosing cholangitis, which is thought to be a familial diseases with different etiology, and steroid responsive biliary strictures be named as immunoglobulin G4 (IgG4)-associated cholangitis (IAC). There is no reliable data regarding effective steroid treatment in autoimmue variant sclerosing cholangitis in Korea. We report a case of 32-year-old male with sclerosing cholangitis, who was diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) and liver biopsy, showing favorable response to prednisolone therapy.
