A Case of Colchicine-induced Acute Myopathy in a Renal Recipient.
- Author:
Ju Yeon CHO
1
;
Jin Ho LEE
;
Hye Young CHOI
;
Yun Kyung KANG
;
Bo Young YOON
;
Seong Hoon HAN
;
Chan Hee LEE
Author Information
1. Departments of Internal Medicine, Inje University College of Medicine, Seoul, Korea. chanheel@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Colchicine;
Myopathy;
Gout;
Renal recipient
- MeSH:
Arthritis, Gouty;
Biopsy;
Colchicine;
Cyclosporine;
Electromyography;
Gout;
Humans;
Kidney Transplantation;
Muscular Diseases*;
Renal Insufficiency
- From:The Journal of the Korean Rheumatism Association
2004;11(4):433-436
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Colchicine is one of the most effective drugs for the treatment of acute gouty arthritis. It can cause myopathy which may be diagnosed by abnormalities of muscle enzyme levels, electromyography, and muscle biopsy, and disappearance of symptoms after drug withdrawal. Colchicine-induced myopathy may be seen in patients with unusually high dose of colchicine, renal insufficiency, combination therapy with cyclosporin, and advanced age. We report a patient who developed acute myopathy after treatment with colchicine for gout which was associated with renal transplantation and cyclosporin treatment.