Prognostic factors in early endometrial cancer: a single institution.
- Author:
Jung Woo PARK
1
;
Byoungick LEE
;
Suk Jin CHOI
;
Jeehyun PARK
;
Sung Ook HWANG
;
Eunseop SONG
Author Information
1. Department of Obstetrics and Gynecology, Inha University College of Medicine, Incheon, Korea.
- Publication Type:Original Article
- Keywords:
Endometrial cancer;
Prognostic factor;
Progress-free survival rate
- MeSH:
Carcinoma, Endometrioid;
Endometrial Neoplasms;
Female;
Humans;
Lymph Node Excision;
Medical Records;
Menopause;
Parity;
Radiotherapy, Adjuvant;
Retrospective Studies;
Survival Rate
- From:Korean Journal of Gynecologic Endoscopy and Minimally Invasive Surgery
2012;24(2):77-83
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To assess the prognostic factors of early endometrial cancer. METHODS: Medical records of patients with endometrial cancer stage I and II were reviewed retrospectively between 1999 and 2005. Progress-free survival rates of each prognostic factor were obtained. RESULTS: The mean age of 45 patients was 49 (27-74). Thirty-nine patients had stage I, 6 patients had stage II of the disease. Most cases of histology were diagnosed with endometrioid adenocarcinoma (42 patients, 93.3%). Twenty-three patients had grade 1, 16 patients had grade 2, and 6 patients had grade 3 histology. Thirty patients had myometrial invasion of less than 50%, while 15 patients had myometrial invasion of more than 50%. Thirty-one patients showed no lympho-vascular space involvement (LVSI), and 14 patients were LVSI positive. All patients were primarily treated by surgery. Twenty-four patients received adjuvant radiotherapy, and 1 patient received concurrent chemotherapy and radiotherapy. In univariate analysis, FIGO stage (p=0.004), tumor grade (p=0.043), myometrial invasion (p=0.030), and LVSI (p=0.003) had statistical significance with PFSR. However, age, parity, menopause, lymphadenectomy, and histology did not. CONCLUSION: Stage, tumor grade, myometrial invasion, and LVSI seemed to be statistical prognostic factors in early endometrial cancer.
