A Case of RhD with Anti-D .
- Author:
Sun Hyung KIM
1
;
Deok Hwa NAM
;
Jin Hyuk YANG
;
Chae Seung LIM
;
Kyoung Un PARK
;
Young Kee KIM
;
Kap No LEE
Author Information
1. Department of Laboratory Medicine, College of Medicine, Korea University, Seoul, Korea. malarim@korea.ac.kr
- Publication Type:Case Report
- Keywords:
RhD;
Genotype;
Partial D
- MeSH:
Exons;
Genotype;
Introns;
Isoantibodies;
Phenotype;
Sequence Analysis, DNA
- From:Korean Journal of Blood Transfusion
2008;19(3):245-249
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report here on a case of a RhD blood group phenotype with anti-D. The RhD phenotype for partial D phenotyping with using six monoclonal anti-sera typed as normal RhD for this case. DNA sequencing analysis of the RhD gene covering intron 8 to exon 10 showed two AAATAAGATA insertion sites in intron 8 and a single nucleotide change in the exon 10 area as compared with the normal RhD gene. However, the functional role of the RhD antigen is unclear.