Hematologic Profiles and Eosinophilia in Very Low Birth Weight Infants.
- Author:
Ji Yeon HAN
1
;
Tae Hwan KIL
;
Jung Min YOON
;
June Bum KIM
;
Kyong Og KO
;
Young Hyuk LEE
;
Jae Woo LIM
Author Information
1. Department of Pediatrics, College of Medicine, Konyang University, Daejeon, Korea. limsoa@hanmail.net
- Publication Type:Original Article
- Keywords:
Very low birth weight infant;
Eosinophilia;
Eosinophil count;
Hematologic profile;
Transfusion
- MeSH:
Blood Cell Count;
Eosinophilia;
Eosinophils;
Gestational Age;
Humans;
Infant;
Infant, Newborn;
Infant, Very Low Birth Weight;
Intensive Care, Neonatal;
Leukocytes;
Logistic Models;
Medical Records;
Neutrophils;
Parenteral Nutrition, Total;
Parturition;
Prevalence
- From:Korean Journal of Perinatology
2011;22(4):285-294
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study investigated the pattern of hematologic profile and eosinophilia for a month after birth in very low birth weight (VLBW) infants. METHODS: The medical records of 141 VLBW infants (birth weight, <1,500 g) admitted to the neonatal intensive care unit (NICU) of Konyang University Hospital. We collected complete blood cell counts (CBC) weekly for 4 weeks and studied hematologic profile and related factors of eosinophilia (> or =700/mm3). RESULTS: Overall, 50.4% of all infants had at least one instance of eosinophilia for a month after birth. There were 50.7% with moderate eosinophilia (1,000-2,999/mm3). White blood cell (WBC) counts and absolute neutrophil count (ANC) climaxed on 7th day of life, whereas eosinophilia mainly occurred on 21st day of life. The demographic data and perinatal characteristics of infants with and without eosinophilia were compared. Prevalence of eosinophilia was associated with gestational age and total parenteral nutrition on 21st day of life; total parenteral nutrition and transfusion on 28th day of life. Eosinophilia was closely associated with transfusion on logistic regression analysis (P<0.05). CONCLUSION: Eosinophilia in VLBW infants occurs mainly on 21st day of life. Eosinophil counts showed a separate trend different from WBC counts and ANC. Transfusion was significantly associated with eosinophilia.
