Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole.
10.9758/cpn.2016.14.2.221
- Author:
Omer BAŞAY
1
;
Burge Kabukcu BASAY
;
Onder ÖZTÜRK
;
Zeki YÜNCÜ
Author Information
1. Department of Child and Adolescent Psychiatry, School of Medicine, Pamukkale University, Denizli, Turkey. burgekabukcu@yahoo.com
- Publication Type:Case Report
- Keywords:
Aripiprazole;
Atomoxetine;
Dystonia
- MeSH:
Adolescent;
Dystonia*;
Female;
Humans;
Male;
Neurotransmitter Agents
- From:Clinical Psychopharmacology and Neuroscience
2016;14(2):221-225
- CountryRepublic of Korea
- Language:English
-
Abstract:
The present report describes the cases of a 17-year-old male patient and a 13-year-old female patient who developed acute dystonia following the administration of low-dose aripiprazole (5 mg/day) after the cessation of atomoxetine treatment. Although aripiprazole-induced dystonia has been previously reported in the literature, it is rare, and most of these cases were associated with doses higher than 5 mg/day. Furthermore, both of the patients in the present study discontinued atomoxetine prior to the initiation of aripiprazole treatment; thus, this report also discussed the possible mechanisms underlying the manifestation of dystonia from the perspective of neurotransmitter activity.