Clinical Efficacy of Nonsurgical Treatment of Crohn's Disease-related Intraabdominal Abscess.
- Author:
Duk Hwan KIM
1
;
Jae Hee CHEON
;
Chang Mo MOON
;
Jae Jun PARK
;
Song Yi HAN
;
Eun Soo KIM
;
Moon Jae CHUNG
;
Jin Ha LEE
;
Min Kyu JUNG
;
Soo Hyun LEE
;
Jung Woo SON
;
Tae Il KIM
;
Won Ho KIM
Author Information
1. Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. geniushee@yuhs.ac
- Publication Type:Original Article ; Comparative Study ; English Abstract
- Keywords:
Crohn's disease;
Inflammatory bowel disease;
Abdominal abscess
- MeSH:
Abdominal Abscess/diagnosis/surgery/*therapy;
Adolescent;
Adult;
Crohn Disease/diagnosis/surgery/*therapy;
Drainage;
Female;
Humans;
Length of Stay;
Male;
Middle Aged;
Predictive Value of Tests;
Recurrence;
Retrospective Studies;
Severity of Illness Index
- From:The Korean Journal of Gastroenterology
2009;53(1):29-35
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: This study was conducted to compare the clinical efficacy between surgical and nonsurgical treatments for patients with Crohn's disease-related intraabdominal abscess. METHODS: A retrospective review of medical records was performed for patients admitted to a single institution due to Crohn's disease-related intraabdominal abscess from February, 1996 to February, 2008. Clinical outcomes were compared between surgical and nonsurgical groups in terms of treatment responses and recurrences. RESULTS: A total of 47 episodes of intraabdominal abscesses in 43 patients (12.7%) were identified from 339 patients with Crohn's disease. Of these, initially, 18 cases (38.3%) underwent surgical treatment and 29 (61.7%) were treated medically (antibiotic treatments with or without percutaneous drainage). The overall treatment response rates of surgical and nonsurgical group were 100% versus 89.7% (p=0.11) and recurrence rates were 27.8% versus 30.8% (p=1.00). Three patients in nonsurgical group (10.3%) showed no response to therapy and ultimately received surgical drainages. The median length of hospitalization in nonsurgical group was shorter than in surgical group (12 and 29.5 days, respectively. p=0.02). CONCLUSIONS: Nonsurgical treatment might be as effective as surgical treatment for the treatment of Crohn's disease-related intraabdominal abscess, especially considering shorter hospital stay.
