Bullous Pemphigoid Responding to DDS.
- Author:
Kwang Soo KIM
;
Ji Soo KIM
;
Kyung Jin RHIM
;
Sook Ja SON
;
Chang Woo LEE
- Publication Type:Case Report
- MeSH:
Blister;
Humans;
Neutrophils;
Pemphigoid, Bullous*;
Prevalence;
Skin;
Skin Diseases;
Sulfapyridine;
Sulfones
- From:Korean Journal of Dermatology
1982;20(6):913-917
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bullous pemphigoid is a chronic and relatively benign subepidermal blistering disease and is generally considered not to be a sulfa-responsive dermatosis. As a rule, bullous dermatosis that excellently responded to sulfapyridine and sulfones was considered by some to be diagnostic of dermstitis herpetiformia. In 1977, Person and Rogers described 6 cases of bullous pemphigoid responded to sulfapyridine and sulfones. These sulfa-responsive cases were younger than ordinary bullous pemphigoid patients and the histopathologic findings showed prevalence of the neutrophilic infiltration. In this report, the patient who diagnosed as bullous pemphigoid by immunofluorescent studies has younger onset (38 years of age) than usual bullous pemphigoid and histopatbologic findings showed dense neutrophilic infiltrations. The patient was treated with 100-200mg of DDS for 2 months and the skin lesions completely disappeared.
