Pregnancy-associated pulmonary embolism during the peripartum period: An 8-year experience at a single center.
10.5468/ogs.2014.57.4.260
- Author:
Min Young LEE
1
;
Moon Young KIM
;
Jung Yeol HAN
;
Jeong Bae PARK
;
Kyung Sang LEE
;
Hyun Mee RYU
Author Information
1. Department of Obstetrics and Gynecology, Cheil General Hospital & Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea. hmryu2012@naver.com
- Publication Type:Original Article
- Keywords:
Peripartum period;
Pregnancy;
Pulmonary;
Thromboembolism
- MeSH:
Cesarean Section;
Delivery of Health Care;
Diagnosis;
Embolism;
Female;
Hospitals, General;
Incidence;
Maternal Age;
Maternal Death;
Maternal Mortality;
Mortality;
Obesity;
Peripartum Period*;
Postpartum Period;
Pregnancy;
Pregnancy, Multiple;
Pulmonary Embolism*;
Risk Factors;
Survival Rate;
Thrombectomy;
Thromboembolism;
Venous Thromboembolism
- From:Obstetrics & Gynecology Science
2014;57(4):260-265
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The purpose of this study was to estimate the incidence, timing of onset, risk factors, and mortality rate of pregnancy-associated pulmonary embolism (PAPE). METHODS: We analyzed PAPE cases that occurred between January 2005 and December 2012 at Cheil General Hospital & Women's Healthcare Center. Those cases that were not confirmed by computed tomography scan or were confirmed as amniotic fuid embolisms were excluded. We analyzed various risk factors such as previous surgery, mode of delivery, maternal age, and obesity in PAPE. RESULTS: There were 57,092 deliveries over 8 years. Of them, 13 cases (0.023%) were diagnosed with PAPE. All cases occurred in the postpartum period after cesarean delivery. There were no cases of PAPE after vaginal deliveries. Of the total cases, 10 cases (76.9%) were diagnosed in the early postpartum period within 48 hours. Eight cases (61.5%) had a history of previous surgery. There were 3 cases (23.1%) of multiple pregnancy and 3 cases (23.1%) of preterm delivery. No cases had a history of venous thromboembolism. Among 13 cases, 10 cases improved with only anticoagulation, 2 cases received surgical thrombectomy, and one case was maternal death. CONCLUSION: Our results indicated that the incidence of PAPE was very low (0.023%) and occurred mainly in the postpartum period after cesarean section. However, its maternal mortality rate was significantly high (7.7%). Therefore, we suggest that immediate diagnosis and prompt treatment should be prioritized for improvement of PAPE patients' survival rate.
