Effects of Intravenous Lidocaine on Extubation Laryngospasm in Children .
10.4097/kjae.1979.12.3.248
- Author:
Woo Sik KIM
1
;
Sook Ja PARK
;
Se Ung CHON
Author Information
1. Department of Anesthesiology, Catholic Medical College, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Adult;
Anesthesia;
Blood Pressure;
Body Weight;
Child*;
Cough;
Heart Rate;
Humans;
Incidence;
Laryngismus*;
Lidocaine*;
Respiratory Insufficiency;
Respiratory Sounds;
Vocal Cords
- From:Korean Journal of Anesthesiology
1979;12(3):248-251
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Laryngospasm is a serious complication which may be seen following extubation in children. During laryngospasm either the true vocal cords or the true and false cords become opposed in the midline and close the gllotis. Intravenous lidocaine has been used in adult patients to prevent cough following extubation. The present study was made to see if intravenous 1% lidocaine, 2mg/kg of body weight, can be safely used to prevent or control extubation laryngospasm in children. Anesthesia was maintained with halothane-N2O-O2, in a semiclosed circuit. In 20 children, a bolus of 1% lidocaine 2mg/kg was injected intravenously two to three minutes prior to extubation; in the other 20 children, extubation was carried out without prior injection of lidocaine. The incidence of laryngospasm, coughing, respiratory depression, and changes of blood pressure, pulse rate were measured. The results were as follows: 1) Two cases of laryngospasm (10%), 11 cases of coughing (55%) and 2 cases of stridor (10%) were observed following extubation in the control group. Blood pressure and pulse rate showed a tendency to increase about 20%, in the control group. 2) One case of laryngospasm (5%) and 4 cases of coughing (20%) were observed following extubation in the lidocaine pretreated group. Incidence of trouble following extubation was markedly reduced (75 to 25%) in the lidocaine pretreated group. Blood pressure and pulse rate showed a tendency to decrease about 15% in the lidocaine pretreated group.
