Efficacy of Veno-Venous Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Failure.
10.3349/ymj.2015.56.1.212
- Author:
Jae Jun LEE
1
;
Sung Mi HWANG
;
Jae Houn KO
;
Hyoung Soo KIM
;
Kyung Soon HONG
;
Hyun Hee CHOI
;
Myung Goo LEE
;
Chang Youl LEE
;
Won Ki LEE
;
Eun Jin SOUN
;
Tae Hun LEE
;
Jeong Yeol SEO
Author Information
1. Department of Anesthesiology, School of Medicine, Hallym University, Chuncheon, Korea.
- Publication Type:Original Article
- Keywords:
Acute respiratory failure;
extracorporeal membrane oxygenation;
mechanical ventilation;
survival rate
- MeSH:
Acute Disease;
Adult;
Cause of Death;
*Extracorporeal Membrane Oxygenation;
Female;
Humans;
Male;
Middle Aged;
Respiratory Insufficiency/complications/*therapy;
Survival Analysis;
Treatment Outcome
- From:Yonsei Medical Journal
2015;56(1):212-219
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The objective of this study was to evaluate our institutional experience with veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory failure (ARF). MATERIALS AND METHODS: From January 2007 to August 2013, 31 patients with severe ARF that was due to various causes and refractory to mechanical ventilation with conventional therapy were supported with VV ECMO. A partial pressure of arterial oxygen (PaO2)/inspired fraction of oxygen (FiO2) <100 mm Hg at an FiO2 of 1.0 or a pH <7.25 due to CO2 retention were set as criteria for VV ECMO. RESULTS: Overall, 68% of patients survived among those who had received VV ECMO with a mean PaO2/FiO2 of 56.8 mm Hg. Furthermore, in trauma patients, early use of ECMO had the best outcome with a 94% survival rate. CONCLUSION: VV ECMO is an excellent, life-saving treatment option in patients suffering from acute and life-threatening respiratory failure due to various causes, especially trauma, and early use of VV ECMO therapy improved outcomes in these patients.
