A Case of Cushing Syndrome Diagnosed by Recurrent Pathologic Fractures in a Young Woman.
10.11005/jbm.2012.19.2.153
- Author:
Ju Young HAN
1
;
Jungjin LEE
;
Gyung Eun KIM
;
Jin Yeob YEO
;
So Hun KIM
;
Moonsuk NAM
;
Yong Seong KIM
;
Seongbin HONG
Author Information
1. Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea. sbhongmd@inha.ac.kr
- Publication Type:Case Report
- Keywords:
Cushing syndrome;
Osteoporotic fractures
- MeSH:
Adult;
Amenorrhea;
Cushing Syndrome;
Edema;
Female;
Fractures, Compression;
Fractures, Spontaneous;
Glucose;
Hirsutism;
Humans;
Hypertension;
Incidence;
Obesity, Abdominal;
Osteoporosis;
Osteoporotic Fractures;
Parathyroid Hormone;
Prevalence;
Spine;
Steroids
- From:Journal of Bone Metabolism
2012;19(2):153-158
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cushing's syndrome is characterized by central obesity, fatigability, weakness, amenorrhea, hirsutism, edema, hypertension, impaired glucose tolerance, and osteoporosis due to excessive production of steroids. Cushing's syndrome is an important cause of secondary osteoporosis. Patients with Cushing's syndrome have a high incidence of osteoporotic fractures. At least, 30-50% of patients with Cushing's syndrome experience fractures, particularly in the vertebral body. And it is consistent with the 50% prevalence of osteoporosis in patients with Cushing's syndrome. However, reports of multiple pathological fractures in young patients with Cushing's syndrome are rare. Thus, we describe the case of a 26-year-old woman with Cushing's syndrome accompanied with recurrent multiple osteoporotic fractures and being treated by parathyroid hormone. Careful consideration for the possibility of Cushing's syndrome will be necessary in case of young patients with a spontaneous multiple compression fractures in spine.
