Comparison of Optical Coherence Tomography Characteristics among Three Subtypes of Exudative Age-related Macular Degeneration.
10.3341/jkos.2016.57.7.1093
- Author:
Soh Eun AHN
1
;
Dong Seob AHN
;
Heon YANG
;
Hee Seong YOON
Author Information
1. Sungmo Eye Hospital, Busan, Korea. heesyoon@dreamwiz.com
- Publication Type:Original Article
- Keywords:
Age-related macular degeneration;
Optical coherence tomography;
Polypoidal choroidal vasculopathy;
Retinal angiomatous proliferation
- MeSH:
Choroid;
Humans;
Macular Degeneration*;
Retinaldehyde;
Retrospective Studies;
Subretinal Fluid;
Tomography, Optical Coherence*
- From:Journal of the Korean Ophthalmological Society
2016;57(7):1093-1101
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To compare the characteristics of optical coherence tomography in eyes with treatment-naïve typical neovascular age-related macular degeneration (typical nAMD), polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP). METHODS: One hundred fifty-three eyes newly diagnosed with exudative AMD were retrospectively collected. All study eyes were classified into three subtypes: typical nAMD, PCV, and RAP. Subfoveal choroidal thickness (SFCT) was measured using enhanced depth imaging optical coherence tomography (EDI-OCT). Central macular thickness (CMT) and other OCT features including intraretinal cystoid fluid and subretinal fluid were also evaluated in all eyes. SFCT, CMT and other OCT features were compared among the three subtypes of exudative AMD. RESULTS: Seventy-four eyes with typical nAMD, 55 eyes with PCV, and 24 eyes with RAP were included. SFCT was significantly thickest in PCV and thinnest in RAP (p < 0.001). RAP showed the thickest CMT and the highest frequency of intraretinal cystoid fluid (p = 0.004, p < 0.001, respectively). CONCLUSIONS: In patients with exudative AMD, different characteristics of OCT were observed according to the three subtypes. Identification of OCT characteristics could help differentiate the subtypes of exudative AMD.
