A Case of Therapeutic Keratoplasty Using Cryo-preservative Cornea in Candida albicans Keratitis.
10.3341/jkos.2016.57.7.1170
- Author:
Jung Yeob HAN
1
;
Jong Hwa JUN
Author Information
1. Department of Ophthalmology, Keimyung University School of Medicine, Daegu, Korea. junjonghwa@gmail.com
- Publication Type:Case Report
- Keywords:
Candida albicans;
Cryopreserved cornea;
Fungal keratitis;
Therapeutic keratoplasty
- MeSH:
Aged;
Ambulatory Care Facilities;
Amphotericin B;
Anterior Chamber;
Candida albicans*;
Candida*;
Cornea*;
Corneal Transplantation*;
Female;
Follow-Up Studies;
Humans;
Inflammation;
Iris;
Keratitis*;
Keratoplasty, Penetrating;
Membranes;
Pigmentation;
Slit Lamp;
Tissue Donors;
Voriconazole
- From:Journal of the Korean Ophthalmological Society
2016;57(7):1170-1175
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case treated with therapeutic keratoplasty using a cryo-preserved cornea in a patient with Candida albicans keratitis. CASE SUMMARY: A 77-year-old female visited our clinic because of left ocular pain and visual disturbance for 3 days. Microscopic slit lamp examination revealed a 1.2 mm sized round corneal epithelial defect with deep stromal infiltration, brownish pigmentation and signs of inflammation with cyclitic membranes in the anterior chamber. On suspicion of Candida keratitis, we performed penetrating keratoplasty using a cryo-preserved donor cornea in Optisol-GS® (Bausch & Lomb, Irvine, CA, USA) solution with excision of the infected iris and colony of the anterior chamber. After the procedure, injection of intravitreal or intracameral amphotericin B and voriconazole were administered alternately. At 2 weeks after the second surgery, infection signs disappeared. At the follow-up in the outpatient clinic, signs of infection were not observed. CONCLUSIONS: Therapeutic keratoplasty using a cryo-preserved donor cornea can be an immediate and effective therapeutic strategy for Candida albicans keratitis.
