Lymphocyte and Serum Immunoglobulin Studies in Behcet's Syndrome.
- Author:
Eun So LEE
;
Dong Sik BANG
;
Seung Hun LEE
;
Sung Nack LEE
- Publication Type:Original Article
- Keywords:
Behcet's syndrome;
Cell mediated immunity;
Humoral immunity
- MeSH:
B-Lymphocytes;
Behcet Syndrome*;
Humans;
Immunity, Cellular;
Immunity, Humoral;
Immunodiffusion;
Immunoglobulin A;
Immunoglobulin G;
Immunoglobulin M;
Immunoglobulins*;
Lymphocyte Activation;
Lymphocytes*;
T-Lymphocytes
- From:Korean Journal of Dermatology
1987;25(6):734-744
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In our investigation, various immunologic aspects of 129 patients with complete and incomplete type of Behcet's syndrome were taken under consideration : quantitation of total T-cells by E-rosette method and B-cells by EAC-rosette method, helper/inducer T and suppressor/cytotoxic T-cells by monoclonal antibody technique(OKT4, OKT8), lymphocyte transformation test with PHA, quantitation of serum r-globulin by electro phoresis and quantitations of serum IgG, IgA, IgM, C3, C4 by immunodiffusion. From the results, the cell mediated immunity in Behcet's syndrome is not influenced by the number of patterns of four major symptoms or the activity of each major symptom at the time of test. However the humoral immunity is considered to be influenced by the above parameters.