A Case of Immunoglobulin E Mediated Anaphylaxis to Levodropropizine.
10.3349/ymj.2013.54.1.262
- Author:
Kyung Hee PARK
1
;
Il Seon YUN
;
Soo Young CHOI
;
Jae Hyun LEE
;
Chein Soo HONG
;
Jung Won PARK
Author Information
1. Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. parkjw@yuhs.ac
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Levodropropizine;
anaphylaxis;
drug hypersensitivity
- MeSH:
Adolescent;
Anaphylaxis/*chemically induced/*immunology;
Antitussive Agents/*adverse effects;
Bronchial Provocation Tests;
Enzyme-Linked Immunosorbent Assay;
Female;
Humans;
Immunoglobulin E/*immunology;
Propylene Glycols/*adverse effects;
Skin Tests
- From:Yonsei Medical Journal
2013;54(1):262-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerable to acetaminophen alone, we thought the culprit agent was maybe a levodropropizine tablet. To confirm the culprit, she underwent skin prick test and oral drug provocation test with the suspected one. Finally we detected levodropropizine specific IgE and confirmed the specificity by inhibition enzyme-linked immunosorbent assay (ELISA).
