A Case of Cycloserine-Induced Lichenoid Drug Eruption Supported by the Lymphocyte Transformation Test.
10.4168/aair.2017.9.3.281
- Author:
Jakyoung KIM
1
;
Shinyoung PARK
;
Chul Min JUNG
;
Chee Won OH
;
Jae Woo KWON
Author Information
1. Department of Pediatrics, Kangwon National University School of Medicine, Chuncheon, Korea.
- Publication Type:Case Report
- Keywords:
Cycloserine;
lichenoid eruptions;
lymphocyte activation;
drug hypersensitivity;
drug eruptions
- MeSH:
Cycloserine;
Diagnosis;
Drug Eruptions*;
Drug Hypersensitivity;
Humans;
Lichenoid Eruptions;
Lymphocyte Activation*;
Lymphocytes*;
Patch Tests
- From:Allergy, Asthma & Immunology Research
2017;9(3):281-284
- CountryRepublic of Korea
- Language:English
-
Abstract:
Lichenoid drug eruption (LDE) is a rare form of delayed-type drug eruption. Among anti-tuberculosis (Tb) agents, cycloserine (CS) has been reported as a rare cause of LDE. Positive results on the lymphocyte transformation test (LTT) have not been reported in patients with LDE. In the present case, we performed LTT and a patch test, and successfully proved CS as the offending drug in this patient, who had been treated with multiple anti-Tb drugs. These observations suggest that CS should be considered a possible cause of LDE and that LTT can be an option for the diagnosis of LDE.
