Alternating Hemispheric Seizures with Migrating Brain Lesions in MELAS Syndrome.
- Author:
So Young MOON
1
;
Seung Bong HONG
;
Young Min SONG
;
Jae Wook RYOO
;
Dae Won SEO
Author Information
1. Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sbhong@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
MELAS;
Seizures;
MRI;
Migratory
- MeSH:
Acidosis, Lactic;
Brain*;
Electroencephalography;
Epilepsy;
Female;
Humans;
Magnetic Resonance Imaging;
MELAS Syndrome*;
Seizures*;
Young Adult
- From:Journal of Korean Epilepsy Society
2002;6(1):73-76
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epileptic seizure is a frequent sign of mitochondrial encephalopathies with lactic acidosis and stroke-like episodes (MELAS). We report a 21-year-old woman with MELAS who had alternating hemispheric seizures. Her brain MRI showed migratory short lasting lesions. Serial EEG recordings revealed epileptiform discharges, which occurred first on the right frontotemporal region but then switched to the left frontotemporal region concordant to her clinical and MRI manifestations. Migratory short lasting lesions may be helpful features for differentiating MELAS syndrome from other epileptic syndromes.