Anticholinesterase Treatment for Patients With Paralytic Strabismus Following a Viper Bite.
10.3341/jkos.2009.50.11.1698
- Author:
Jung Ho LEE
1
;
Sung Min AHN
;
Bo Young JUNG
Author Information
1. Department of Ophthalmology, Dongguk University Gyeongju Hospital, Gyeongju, Korea. letter0116@naver.com
- Publication Type:Original Article
- Keywords:
Anticholinesterase;
Blepharoptosis;
Paralytic strabismus;
Snake bite
- MeSH:
Anti-Bacterial Agents;
Bites and Stings;
Blepharoptosis;
Diplopia;
Humans;
Prospective Studies;
Snake Bites;
Strabismus;
Stress, Psychological;
Tetanus Toxoid
- From:Journal of the Korean Ophthalmological Society
2009;50(11):1698-1704
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To describe the therapeutic effect of anticholinesterase treatment for patients with paralytic strabismus and blepharoptosis following a viper bite METHODS: A prospective non-comparative interventional case series study was designed including 6 patients with ophthalmic complications such as paralytic strabismus and blepharoptosis following a viper bite. Anticholinesterase (pyridostigmine) 60 mg was administered to patients 3 times a day in additional to conservative treatment including antivenom, antibiotics and tetanus toxoid. Patients underwent a measurement of deviation, diplopia test and MRD 1. Subjective evaluation of the diplopia symptoms was performed daily after treatment. RESULTS: Subjective diplopia was relieved in 2 out of the 6 patients on the first day and in the other 4 patients on the second day. The angle of deviation decreased approximately 37% on the first day and ocular position became orthophoric on the third day in all patients. The blepharoptosis was completely resolved in 4 patients on the first day. No complication following anticholinesterase treatment was noticed. CONCLUSIONS: Treatment using anticholinesterase for patients suffering from diplopia and blepharoptosis following a viper bite is an effective and safe treatment.
