A Case of Burkholderia cepacia Bacteremia and Infective Spondylitis, Treated with Ceftazidime and Trimethoprim-Sulfamethoxazole Combination Therapy, which did not Respond to Carbapenem Monotherapy.
- Author:
Mi Ok JANG
1
;
Hyun Wook KANG
;
Seong Eun KIM
;
Seung Ji KANG
;
Hee Chang JANG
;
Sook In JUNG
;
Jong Hee SHIN
;
Kyung Hwa PARK
Author Information
- Publication Type:Case Report
- Keywords: Burkholderia cepacia; Spondylitis
- MeSH: Abscess; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Burkholderia; Burkholderia cepacia; Ceftazidime; Disinfectants; Spondylitis; Trimethoprim, Sulfamethoxazole Drug Combination
- From:Infection and Chemotherapy 2011;43(6):490-493
- CountryRepublic of Korea
- Language:Korean
- Abstract: Burkholderia cepacia is an aerobic gram-negative rod that causes healthcare-associated infections through contaminated disinfectants, fluids, and medical equipment. This bacterium shows resistance to various antibiotics. For this reason, available therapeutic antimicrobial agents are limited, and the optimal antimicrobial therapeutic regimen was still not well-determined in the case of infective spondylitis. We experienced a case of B. cepacia bacteremia with infective spondylitis and paraspinal abscesses which did not respond to carbapenem monotherapy, but was did respond to ceftazidime and sulfamethoxzaole/trimethoprim combination therapy.