Characterization of Peripapillary Atrophy Using Spectral Domain Optical Coherence Tomography.
10.3341/kjo.2010.24.6.353
- Author:
Jung Hwa NA
1
;
Byung Gil MOON
;
Kyung Rim SUNG
;
Youngrok LEE
;
Michael S KOOK
Author Information
1. Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sungeye@gmail.com
- Publication Type:Original Article ; Case Reports
- Keywords:
Bruch's membrane;
Glaucoma;
Peripapillary atrophy;
Retinal nerve fiber layer;
Spectral-domain optical coherence tomography
- MeSH:
Adult;
Aged;
Bruch Membrane/pathology;
Female;
Glaucoma/*complications;
Humans;
Male;
Middle Aged;
Nerve Fibers/pathology;
Optic Atrophy/*diagnosis/*etiology;
Optic Disk/*pathology;
Photoreceptor Cells, Vertebrate/pathology;
Retina/pathology;
Retinal Pigment Epithelium/pathology;
Tomography, Optical Coherence/*methods
- From:Korean Journal of Ophthalmology
2010;24(6):353-359
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To characterize the features of peripapillary atrophy (PPA), as imaged by spectral-domain optical coherence tomography (SD-OCT). METHODS: SD-OCT imaging of the optic disc was performed on healthy eyes, eyes suspected of having glaucoma, and eyes diagnosed with glaucoma. From the peripheral beta-zone, the retinal nerve fiber layer (RNFL), the junction of the inner and outer segments (IS/OS) of the photoreceptor layer, and the Bruch's membrane/retinal pigment epithelium complex layer (BRL) were visualized. RESULTS: Nineteen consecutive eyes of 10 subjects were imaged. The RNFL was observed in the PPA beta-zone of all eyes, and no eye showed an IS/OS complex in the beta-zone. The BRL was absent in the beta-zone of two eyes. The BRL was incomplete or showed posterior bowing in the beta-zone of five eyes. CONCLUSIONS: The common findings in the PPA beta-zone were that the RNFL was present, but the photoreceptor layer was absent. Presence of the BRL was variable in the beta-zone areas.
