Relationship Between Bone Mineral Density and Body Composition in Pre- and Post-menopausal Korean Women.
- Author:
Eun Young CHOI
- Publication Type:Original Article
- Keywords:
Bone mineral density;
Body composition;
Osteoporosis;
Dual energy X-ray absorptiometry
- MeSH:
Absorptiometry, Photon;
Body Composition;
Bone Density;
Confounding Factors (Epidemiology);
Female;
Femur Neck;
Humans;
Korea;
Linear Models;
Nutrition Surveys;
Osteoporosis;
Osteoporosis, Postmenopausal;
Spine;
Weights and Measures
- From:Korean Journal of Health Promotion
2013;13(2):52-60
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: To investigate the relationship between body composition and bone mineral density (BMD) in preand post-menopausal women in Korea. METHODS: The data of 4,334 pre- and post-menopausal women older than 20 years from the Korea National Health and Nutrition Examination Survey conducted in 2008-2009 were assessed. BMD and body composition were measured by dual-energy X-ray absorptiometry. All analyses except stepwise multiple linear regression analysis were performed using the KNHANES sample weights to account for the complex survey design. RESULTS: After adjusting for confounding variables, lean mass and fat mass were positively correlated with BMD at both L1-4 spine and femur neck in both pre- and post-menopausal women (P<0.001). For the pre-menopausal women, lean mass was the most important determinant of BMD at both sites (R2=0.156 for L1-4 spine BMD, R2=0.168 for femur neck BMD), and the impact of fat mass were minimal. For the post-menopausal women, fat mass had a greater influence on the BMD at L1-4 spine than lean mass (R2=0.016 vs. R2=0.077), but lean mass had a greater impact than fat mass on the BMD at the femur neck (R2=0.077 vs. R2=0.007). After adjusting for confounding variables, post-menopausal osteoporosis increased as both lean mass and fat mass decreased (P(trend)<0.001). CONCLUSIONS: In Korean pre- and post-menopausal women, both lean mass and fat mass had positive correlations with the BMD at both sites and decreased the risk of osteoporosis. Lean mass had a greater influence on premenopausal BMD at both sites and postmenopausal BMD at the femur neck, whereas fat mass had greater influence on post-menopausal BMD at L1-4 spine.
