Co-occurrence of Guillain-Barré Syndrome and Acute Disseminated Encephalomyelitis with Dual Positive of Anti-GT1a and Anti-GM1 Antibodies.
- Author:
Juyoung LEE
1
;
Jinhyuk YOO
;
Dong Gook KANG
;
Yerim KIM
;
Byeol A YOON
;
Jong Kuk KIM
;
Jong Seok BAE
Author Information
- Publication Type:Case Report
- Keywords: Acute disseminated encephalomyelitis; Guillain-Barré syndrome; Gangliosides
- MeSH: Antibodies*; Brain Diseases; Encephalomyelitis, Acute Disseminated*; Gangliosides; Guillain-Barre Syndrome*; Humans; Immunoglobulin G; Immunoglobulin M; Incidence; Magnetic Resonance Imaging; Male; Nervous System Diseases; Paralysis; Peripheral Nervous System; Young Adult
- From:Journal of the Korean Neurological Association 2017;35(4):211-214
- CountryRepublic of Korea
- Language:Korean
- Abstract: Acute disseminated encephalomyelitis (ADEM) and Guillain-Barré syndrome (GBS) are both rare post-infectious neurological disorders. The co-existence of these conditions has often been reported despite of low incidence. We describe a 20-year-old male, who presented with acute flaccid paralysis and encephalopathy. The patient showed reversible MRI lesions suggesting ADEM. This case showed anti-GT1a IgG and anti-GM1 IgM antibodies positivity. We suggest that certain immunogenicity within central and peripheral nervous system may share a common autoimmune process during the disease course.
