A Case of Behcet's Disease Associated with Schizophrenia and Myelodysplastic Syndrome with Trisomy 8 and 9.
10.4078/jrd.2013.20.6.369
- Author:
Jung Hoon BAEK
1
;
Hyun Jung CHUN
;
Youn Hee PARK
;
Jeong Hyeon CHO
;
Sang Kyun BAE
;
You Jung HA
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Kwandong University College of Medicine, Myongji Hospital, Goyang, Korea. haayou@hanmail.net
- Publication Type:Case Report
- Keywords:
Behcet's disease;
Myelodysplastic syndrome;
Schizophrenia
- MeSH:
Abdominal Pain;
Anemia;
Bone Marrow;
Colonoscopy;
Fever;
Humans;
Middle Aged;
Myelodysplastic Syndromes*;
Schizophrenia*;
Thrombocytopenia;
Trisomy*;
Ulcer
- From:Journal of Rheumatic Diseases
2013;20(6):369-373
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Behcet's disease (BD) is a multi-systemic inflammatory disease of unknown origin that affects nearly all organs. Recent reports of BD with myelodysplastic syndrome (MDS) often note an association with gastrointestinal involvement and trisomy 8. We herein report on a case of a 51-year-old man who had refractory schizophrenia and developed gastrointestinal BD and MDS with trisomy 8 and 9. He visited our hospital due to fever and abdominal pain. Multiple ulcerations in the colorectum were observed on colonoscopy, and he was diagnosed with intestinal BD. During the treatment of intestinal BD, anemia and thrombocytopenia developed. His bone marrow study revealed myelodysplastic syndrome (refractory anemia with ringed sideroblast) with trisomy 8 and trisomy 9. We report a rare case of intestinal BD accompanied by schizophrenia and myelodysplastic syndrome with trisomy 8 and 9.
