Flow Cytometric DNA Analysis in Colorectal Cancer and Its Relationship to.
- Author:
Dong Ho CHOI
1
;
Tae Sung SOHN
;
Young Buk PARK
;
Hong Kyu BAIK
;
Young Soo NAM
Author Information
1. Department of Surgery, Hanyang University, College of Medicine.
- Publication Type:Original Article
- Keywords:
Flow Cytometry
- MeSH:
Aneuploidy;
Colorectal Neoplasms*;
Diploidy;
DNA*;
Flow Cytometry;
Humans;
Lymph Nodes;
Neoplasm Metastasis;
Ploidies;
Prognosis;
Survival Rate
- From:Journal of the Korean Society of Coloproctology
1997;13(1):23-30
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
DNA flow cytometric analysis was performed on 42 colorectal cancers. DNA ploidy was diploid in 19 and aneuploid in 23 cases. There was no significant correlation between DNA ploidy and clinicopathological features such as primary site, histologic type, depth of invasion, lymph node metastasis, peritoneal seedings, lymphatic invasion and vascular invasion. In aneuploid group, which was divided into two groups, by the value of DNA index, there was no differences between two groups in prognosis and clinocoPathological features. Cumulative survival rates appeared to be more favorable in patients with aneuploid tumors than patients with diploid tumors, but the difference was not statistically significant.
