5-Fluorouracil and Glaucoma Filtering Surgery: I. Delayed administration.
- Author:
Dong Myung KIM
1
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Fibroblasts;
Filtering Surgery*;
Fluorouracil*;
Glaucoma*;
Wound Healing;
Wounds and Injuries
- From:Journal of the Korean Ophthalmological Society
1987;28(6):1309-1314
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
As fibroblasts proliferation at the sclerectomy wound is known to be vigorous after the fifth or sixth postoperative day, this study was performed to know if a delay in the administration of 5-fluorouracil until this time can still interfere with fibroblasts proliferation. The delayed onset of administration was seem to be efficacious. If this is more confirmed at further study, a decreased dose of postoperative 5-fluorouracil may interfere less with corneal wound healing.
