Radiofrequency Ablation Treatment for Renal Cell Carcinoma: Early Clinical Experience.
- Author:
Seong Hoon PARK
1
;
Seong Kuk YOON
;
Jin Han CHO
;
Jong Young OH
;
Kyung Jin NAM
;
Hee Jin KWON
;
Su Yeon KIM
;
Myong Jin KANG
;
Sunseob CHOI
;
Gyung Tak SUNG
Author Information
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords: Radiofrequency ablation; Renal tumors; Kidney tumors
- MeSH: Adult; Aged; Carcinoma, Renal Cell/radiography/*surgery; *Catheter Ablation/adverse effects; Female; Humans; Kidney Neoplasms/radiography/*surgery; Male; Middle Aged; Tomography, X-Ray Computed
- From:Korean Journal of Radiology 2008;9(4):340-347
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To evaluate the early clinical experience associated with radiofrequency (RF) ablation in patients with renal cell carcinoma (RCC). MATERIALS AND METHODS: The RF ablation treatment was performed on 17 tumors from 16 patients (mean age, 60.5 years; range, 43-73 years) with RCC. The treatment indications were localized, solid renal mass, comorbidities, high operation risk, and refusal to perform surgery. All tumors were treated by a percutaneous CT (n = 10), followed by an US-guided (n = 2), laparoscopy-assisted US (n = 2), and an open (n = 2) RF ablation. Furthermore, patients underwent a follow-up CT at one day, one week, one month, three and six months, and then every six months from the onset of treatment. We evaluated the technical success, technical effectiveness, ablation zone, benign periablation enhancement, irregular peripheral enhancement, and complications. RESULTS: All 17 exophytic tumors (mean size, 2.2 cm; range, 1.1-5.0 cm) were completely ablated. Technical success and effectiveness was achieved in all cases and the mean follow-up period was 23.8 months (range, 17-33 months). A local recurrence was not detected in any of the cases; however, five patients developed complications as a result of treatment, including hematuria (n = 2), mild thermal injury of the psoas muscle (n = 1), mild hydronephrosis (n = 1), and fistula formation (n = 1). CONCLUSION: The RF ablation is an alternative treatment for exophytic RCCs and represents a promising treatment for some patients with small RCCs.
