Improvement of Screening Accuracy of Mini-Mental State Examination for Mild Cognitive Impairment and Non-Alzheimer's Disease Dementia by Supplementation of Verbal Fluency Performance.
- Author:
Jee Wook KIM
1
;
Dong Young LEE
;
Eun Hyun SEO
;
Bo Kyung SOHN
;
Young Min CHOE
;
Shin Gyeom KIM
;
Shin Young PARK
;
IL Han CHOO
;
Jong Chul YOUN
;
Jin Hyeong JHOO
;
Ki Woong KIM
;
Jong Inn WOO
Author Information
1. Department of Neuropsychiatry, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Republic of Korea.
- Publication Type:Original Article
- Keywords:
Mini-Mental State Examination;
Verbal fluency;
Screening accuracy;
Mild cognitive impairment;
Non-Alzheimer's disease dementia
- MeSH:
Alzheimer Disease;
Animals;
Dementia*;
Mass Screening*;
Mild Cognitive Impairment*;
NAD
- From:Psychiatry Investigation
2014;11(1):44-51
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: This study aimed to investigate whether the supplementation of Verbal Fluency: Animal category test (VF) performance can improve the screening ability of Mini-Mental State Examination (MMSE) for mild cognitive impairment (MCI), dementia and their major subtypes. METHODS: Six hundred fifty-five cognitively normal (CN), 366 MCI [282 amnestic MCI (aMCI); 84 non-amnestic MCI (naMCI)] and 494 dementia [346 Alzheimer's disease (AD); and 148 non-Alzheimer's disease dementia (NAD)] individuals living in the community were included (all aged 50 years and older) in the study. RESULTS: The VF-supplemented MMSE (MMSE+VF) score had a significantly better screening ability for MCI, dementia and overall cognitive impairment (MCI plus dementia) than the MMSE raw score alone. MMSE+VF showed a significantly better ability than MMSE for both MCI subtypes, i.e., aMCI and naMCI. In the case of dementia subtypes, MMSE+VF was better than the MMSE alone for NAD screening, but not for AD screening. CONCLUSION: The results support the usefulness of VF-supplementation to improve the screening performance of MMSE for MCI and NAD.
