A case of intravenous immunoglobulin therapy in severe aspirin - sensitive asthma patient combined with IgG1 and IgG3 subclass deficiency.
- Author:
Hae Sim PARK
;
Hee Yeon KIM
;
Dong Ho NAHM
;
Sang Yong YOO
;
Sung Gyun AHN
;
Dong Suk HAN
- Publication Type:Case Report
- Keywords:
asthma;
IgG subclass deficiency;
intravenous immunoglobulin
- MeSH:
Aspirin*;
Asthma*;
Humans;
Immunization, Passive*;
Immunoglobulin G*;
Immunoglobulins*;
Lung Diseases;
Pneumonia;
Respiratory Tract Infections;
Young Adult
- From:Journal of Asthma, Allergy and Clinical Immunology
1999;19(4):610-614
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Common complications in a patient with IgG subclass deficiency include recurrent respiratory infections and concomitant inflammatory lung disease. The most effective therapy in these patients is the administration of intravenous immunoglobulin. The authors report a case of severe aspirin-sensitive asthma and recurrent pneumonia with combined IgG1, and IgG3 subclass deficiency in a 19-year-old man. The patient was treated with 0.4g/kg at monthly intervals for 6 months, and is still receiving 0.2g/kg every 2 weeks at our clinic. After the replacement of intravenous immunoglobulin, the patient has clinically improved.
