A Case of Rectal Gastrointestinal Stromal Tumor with Bleeding.
- Author:
Jeong Ah SHIN
1
;
Seong Jun KIM
;
Won Chang SHIN
;
Jin Ho LEE
;
Won Choong CHOI
;
Kwan Yeop KIM
;
Myeong Ja JEONG
;
Sung Jig LIM
Author Information
1. Department of Internal Medicine, Inje University College of Medicine, Seoul, Korea. choi829@sanggyepaik.ac.kr
- Publication Type:Case Report
- Keywords:
GIST;
Rectum;
KIT;
CD34
- MeSH:
Aged;
Biopsy;
Female;
Gastrointestinal Stromal Tumors*;
Gastrointestinal Tract;
Hemorrhage*;
Humans;
Neoplasm Metastasis;
Rectum;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
2005;30(3):173-177
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gastrointestinal stromal tumors (GIST), although uncommon mesenchymal tumors of the gastrointestinal tract, are occasionally encountered on endoscopic examination. GIST can be found all gastrointestinal tract, but rare in the rectum. We report a 72-year-old woman presented with intermittent bloody stool for a year. On rectal examination, a firm fixed mass was felt on the anterior wall of the rectum. Computed tomography revealed the 4.8x4.5 cm sized exophytic and centrally depressed mass on the rectum without the evidence of adjacent organ invasion or metastasis. On colonoscopic examination, there was a round elevated lesion having central ulcer with adherent blood clots. Endoscopic deep biopsy examination revealed a submucosal tumor consisting of spindle cells with elongated cigar-shaped nuclei arranged in fascicles and whorls. Mitotic counts were fewer than 5 per 50 high-power fields. The tumor cells were positive for KIT and CD34 immunohistostaining and negative for SMA. Local excision recommended, but the patient discharged against the advice.
