Epidemiologic and Clinical Features of Uveal Melanoma in Korean Patients.
10.3341/jkos.2008.49.8.1289
- Author:
Jeong Hun BAE
1
;
Won Kyung SONG
;
Hyoung Jun KOH
;
Oh Woong KWON
;
Sung Chul LEE
Author Information
1. Department of Ophthalmology, The Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea. sunglee@yuhs.ac.kr
- Publication Type:Original Article
- Keywords:
Clinical feature;
Epidemiology;
Korean patients;
Uveal melanoma
- MeSH:
Eye;
Female;
Humans;
Male;
Medical Records;
Melanoma;
Retrospective Studies;
Uveal Neoplasms;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2008;49(8):1289-1296
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the epidemiologic and clinical features of uveal melanomas in Korean patients. METHODS: The medical records of 35 patients (35 eyes) with the diagnosis of uveal melanoma between September 2004 and December 2006 were reviewed retrospectively. RESULTS: Of the 35 patients, 22 were males (62.9%) and 13 were females (37.1%), with a mean age at diagnosis of 48.2+/-14.1 years (range, 24-82 years). Decreased visual acuity was the most common symptom in 23 patients (65.7%), while 6 patients (17.1%) were detected without prior symptoms. The shape of the uveal melanoma was dome-shaped in 27 eyes (77.1%) and mushroom-shaped in 8 eyes (22.9%). The mean largest basal diameter of the tumors was 9.0+/-3.3 mm (2.4-19.0 mm), and the mean apical height was 6.2+/-2.6 mm (1.1-13.0 mm). The tumors were classified according to their size; a small melanoma was found in 4 eyes (11.4%), a medium melanoma in 29 eyes (82.9%), and a large melanoma in 2 eyes (5.7%). CONCLUSIONS: Uveal melanomas manifest earlier in Korean patients than in Caucasian patients. At the time of diagnosis, 33 eyes (94.3%) had small or medium melanomas that could be treated.
