Chondrosarcoma Arising from Benign Bone Tumor due to Malignant Transformation.
10.5292/jkbjts.2011.17.1.17
- Author:
Wan hyeong CHO
;
Won Seok SONG
;
Chang Bae KONG
;
Yun Suk HONG
;
Jung Dong LEE
;
Dae Geun JEON
- Publication Type:Original Article
- Keywords:
chondrosarcoma;
maliganant transformation;
prognostic factor
- MeSH:
Chondrosarcoma;
Disease-Free Survival;
Enchondromatosis;
Follow-Up Studies;
Humans;
Neoplasm Metastasis;
Osteochondroma;
Osteochondromatosis;
Prognosis;
Recurrence;
Retrospective Studies
- From:The Journal of the Korean Bone and Joint Tumor Society
2011;17(1):17-22
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We analyzed the oncological outcome and prognostic factor of the chondrosarcoma arising from benign bone tumor due to malignant transformation. MATERIALS AND METHODS: From April 1986 to April 2009, 18 cases were considered eligible. We analyzed retrospectively the patient's characteristics and prognostic factors that affect to the local recurrence and distant metastasis. RESULTS: As classified by primary benign bone tumor, 4 cases were solitary osteochondroma, 11 cases were multiple osteochondromatosis and 3 cases were multiple enchondromatosis. The mean follow-up period was 85 months. The 5-year disease free survival rate of 18 patients was 85.9%. Their overall MSTS score was 25.2 (84%). There were local recurrence in 3 cases and no distant metastasis. We found that tumor location and surgical margin affected to the prognosis significantly. CONCLUSION: In secondary chondrosarcoma patients, the prognosis was good relatively and tumor location and surgical margin are important prognosis factor.
