A Case of Chronic Inflammatory Demyelinating Polyneuropathy in Lupas Nephritis.
- Author:
Bum Joon PARK
1
;
Hyang KIM
;
Eun Me PARK
;
Hyun Seung KIM
;
Kyu Beck LEE
;
Han Bo LEE
;
Chan Pill PARK
;
Moon Hyang PARK
;
Jun LEE
;
Jae In OH
;
Sang Jong LEE
Author Information
1. Department of Internal Medicine, Sungkuynkwan University School of Medicine, Kangbuk Samsung Hospital, Korea.
- Publication Type:Case Report
- Keywords:
Systemic lupus erithematosus;
Chro-nic inflammatory demyelinating poly-neuropathy;
Sural nerve biopsy
- MeSH:
Adult;
Biopsy;
Humans;
Kidney;
Lupus Nephritis;
Muscle Weakness;
Nephritis*;
Neural Conduction;
Peripheral Nervous System Diseases;
Polyneuropathies*;
Proteinuria;
Sural Nerve
- From:Korean Journal of Nephrology
2000;19(3):558-562
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus(SLE) is a multisys-temic disease. Peripheral neuropathy occurs in about 10% of patients with SLE. Chronic inflammatory demyelinating polyneurpathy has been reported rarely in SLE. We experienced a case of chronic inflammatory polyneuropathy in lupus nephritis. 32-year-old housewife presented to chronic progressive muscle weakness and heavy proteinuria. Kidney biopsy showed compatible with lupus nephritis (WHO Class V, membranous nephropathy). Nerve conduction studies showed reduction in conduction velocity and sural nerve biopsy revealed demyeli-nating polyneuropathy. Steroid therapy led to improvement in clinical symptoms and proteinuria.
